Phasing from an envelope
نویسندگان
چکیده
منابع مشابه
Phasing from an envelope.
Solution of the phase problem is central to crystallographic structure determination. Conventional molecular-replacement methods are ineffective in the absence of knowledge of the structure of a homologous protein. A recent method utilizing the low-resolution molecular shape determined from solution X-ray scattering data has been shown to be successful in locating the molecular shape within the...
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X-ray crystallography and NMR are complementary tools in structural biology. However, it is often difficult to use NMR structures as search models in molecular replacement (MR) to phase crystallographic data. In this study, a new approach is reported utilizing a molecular envelope of NMR structures for MR phasing with the program FSEARCH at low resolution (about 6 Å). Several targets with both ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section D Biological Crystallography
سال: 2001
ISSN: 0907-4449
DOI: 10.1107/s0907444901009374